5533 : 5-[(benzenesulfonyl)({7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl})fluoromethyl]-N,N-dimethyl-1,2,4-oxadiazol-3-amine
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5533 |
| Name | 5-[(benzenesulfonyl)({7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl})fluoromethyl]-N,N-dimethyl-1,2,4-oxadiazol-3-amine |
| smile | C1(C(S(C2=CC=CC=C2)(=O)=O)(C2=NC(N(C)C)=NO2)F)CC2=C(C3=CC(=CC=C3N2)Cl)C1 |
| weight | 475 |
| scaffold ID | 236 |
| scaffold smile | O=S(=O)(c1ccccc1)C(c1ncno1)C1Cc2[nH]c3ccccc3c2C1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 5533 | 5-[(benzenesulfonyl)({7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl})fluoromethyl]-N,N-dimethyl-1,2,4-oxadiazol-3-amine | 0.12 |
Scaffold Activities Statistic