5557 : methyl 2-[2-[N-ethyl-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)anilino]-2-phenylethoxy]acetate (anilinohexafluoroisopropanol 47)
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5557 |
| Name | methyl 2-[2-[N-ethyl-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)anilino]-2-phenylethoxy]acetate (anilinohexafluoroisopropanol 47) |
| smile | CCN(C(C1=CC=CC=C1)COCC(OC)=O)C1=CC=C(C(O)(C(F)(F)F)C(F)(F)F)C=C1 |
| weight | 479 |
| scaffold ID | 247 |
| scaffold smile | c1ccc(CNc2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 5557 | methyl 2-[2-[N-ethyl-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)anilino]-2-phenylethoxy]acetate (anilinohexafluoroisopropanol 47) | 0.9 |
Scaffold Activities Statistic