5601 : tert-butyl 2-[4-[2-[(5-pyridin-2-ylthiophen-2-yl)sulfonylamino]ethyl]phenyl]indole-1-carboxylate (Boc-indole derivate 16)
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5601 |
| Name | tert-butyl 2-[4-[2-[(5-pyridin-2-ylthiophen-2-yl)sulfonylamino]ethyl]phenyl]indole-1-carboxylate (Boc-indole derivate 16) |
| smile | CC(OC(N1C2=CC=CC=C2C=C1C1=CC=C(CCNS(C2=CC=C(C3=CC=CC=N3)S2)(=O)=O)C=C1)=O)(C)C |
| weight | 560 |
| scaffold ID | 1299 |
| scaffold smile | O=S(=O)(NCCc1ccc(-c2cc3ccccc3[nH]2)cc1)c1ccc(-c2ccccn2)s1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 5601 | tert-butyl 2-[4-[2-[(5-pyridin-2-ylthiophen-2-yl)sulfonylamino]ethyl]phenyl]indole-1-carboxylate (Boc-indole derivate 16) | 0.23 |
Scaffold Activities Statistic