5619 : 2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5619 |
| Name | 2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid |
| smile | C1=CC=C(C(C2=CC=CC=C2)CN(CC2=C(Cl)C(C(F)(F)F)=CC=C2)CCCOC2=CC=CC(CC(O)=O)=C2)C=C1 |
| weight | 582 |
| scaffold ID | 147 |
| scaffold smile | c1ccc(CN(CCCOc2ccccc2)CC(c2ccccc2)c2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 5619 | 2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid | 0.03 |
Scaffold Activities Statistic