5631 : 5-(4-chlorophenyl)-3-(2,4,6-trifluorobenzoyl)-2-[2-(trifluoromethoxy)phenyl]-2,3-dihydro-1,3,4-thiadiazole
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5631 |
| Name | 5-(4-chlorophenyl)-3-(2,4,6-trifluorobenzoyl)-2-[2-(trifluoromethoxy)phenyl]-2,3-dihydro-1,3,4-thiadiazole |
| smile | C1=CC=C(OC(F)(F)F)C(C2N(C(C3=C(F)C=C(F)C=C3F)=O)N=C(C3=CC=C(Cl)C=C3)S2)=C1 |
| weight | 517 |
| scaffold ID | 417 |
| scaffold smile | O=C(c1ccccc1)N1N=C(c2ccccc2)SC1c1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 5631 | 5-(4-chlorophenyl)-3-(2,4,6-trifluorobenzoyl)-2-[2-(trifluoromethoxy)phenyl]-2,3-dihydro-1,3,4-thiadiazole | 3.4 |
Scaffold Activities Statistic