5641 : 5-(4-chlorophenyl)-2-(2-methoxyphenyl)-3-(2,4,6-trifluorobenzoyl)-2,3-dihydro-1,3,4-thiadiazole
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5641 |
| Name | 5-(4-chlorophenyl)-2-(2-methoxyphenyl)-3-(2,4,6-trifluorobenzoyl)-2,3-dihydro-1,3,4-thiadiazole |
| smile | COC1=CC=CC=C1C1N(C(C2=C(F)C=C(F)C=C2F)=O)N=C(C2=CC=C(Cl)C=C2)S1 |
| weight | 463 |
| scaffold ID | 417 |
| scaffold smile | O=C(c1ccccc1)N1N=C(c2ccccc2)SC1c1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 5641 | 5-(4-chlorophenyl)-2-(2-methoxyphenyl)-3-(2,4,6-trifluorobenzoyl)-2,3-dihydro-1,3,4-thiadiazole | 0.035 |
Scaffold Activities Statistic