5645 : 3-[5-(4-fluorophenyl)-3-(2,4,6-trifluorobenzoyl)-2,3-dihydro-1,3,4-thiadiazol-2-yl]-2-methoxypyridine
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5645 |
| Name | 3-[5-(4-fluorophenyl)-3-(2,4,6-trifluorobenzoyl)-2,3-dihydro-1,3,4-thiadiazol-2-yl]-2-methoxypyridine |
| smile | COC1=C(C2N(C(C3=C(F)C=C(F)C=C3F)=O)N=C(C3=CC=C(F)C=C3)S2)C=CC=N1 |
| weight | 447 |
| scaffold ID | 1376 |
| scaffold smile | O=C(c1ccccc1)N1N=C(c2ccccc2)SC1c1cccnc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 5645 | 3-[5-(4-fluorophenyl)-3-(2,4,6-trifluorobenzoyl)-2,3-dihydro-1,3,4-thiadiazol-2-yl]-2-methoxypyridine | 0.21 |
Scaffold Activities Statistic