5650 : 3-(2,6-difluoro-4-methoxybenzoyl)-2-(2,3-dimethoxyphenyl)-5-(4-fluorophenyl)-2,3-dihydro-1,3,4-thiadiazole
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5650 |
| Name | 3-(2,6-difluoro-4-methoxybenzoyl)-2-(2,3-dimethoxyphenyl)-5-(4-fluorophenyl)-2,3-dihydro-1,3,4-thiadiazole |
| smile | COC1=CC=CC(C2N(C(C3=C(F)C=C(OC)C=C3F)=O)N=C(C3=CC=C(F)C=C3)S2)=C1OC |
| weight | 488 |
| scaffold ID | 417 |
| scaffold smile | O=C(c1ccccc1)N1N=C(c2ccccc2)SC1c1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 5650 | 3-(2,6-difluoro-4-methoxybenzoyl)-2-(2,3-dimethoxyphenyl)-5-(4-fluorophenyl)-2,3-dihydro-1,3,4-thiadiazole | 0.17 |
Scaffold Activities Statistic