5857 : 3-[(E)-2-[2-chloro-4-[[3-(2-chloro-4-methylsulfonylphenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]ethenyl]benzoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5857 |
| Name | 3-[(E)-2-[2-chloro-4-[[3-(2-chloro-4-methylsulfonylphenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]ethenyl]benzoic acid |
| smile | ClC1C=C(C=CC=1C1C(COC2C=CC(/C=C/C3C=CC=C(C(=O)O)C=3)=C(C=2)Cl)=C(C(C)C)ON=1)S(C)(=O)=O |
| weight | 586 |
| scaffold ID | 480 |
| scaffold smile | C(=Cc1ccc(OCc2conc2-c2ccccc2)cc1)c1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H4 | Bile acid receptor | 5857 | 3-[(E)-2-[2-chloro-4-[[3-(2-chloro-4-methylsulfonylphenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]ethenyl]benzoic acid | 0.0 |
Scaffold Activities Statistic