5861 : 6-[4-[[3-(3-chloro-1-methyl-2-oxopyridin-4-yl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]-2-methylphenyl]-1-methylindole-3-carboxylic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5861 |
| Name | 6-[4-[[3-(3-chloro-1-methyl-2-oxopyridin-4-yl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]-2-methylphenyl]-1-methylindole-3-carboxylic acid |
| smile | ClC1C(N(C)C=CC=1C1C(COC2C=CC(=C(C)C=2)C2C=CC3C(C(=O)O)=CN(C)C=3C=2)=C(C(C)C)ON=1)=O |
| weight | 546 |
| scaffold ID | 208 |
| scaffold smile | O=c1cc(-c2nocc2COc2ccc(-c3ccc4cc[nH]c4c3)cc2)cc[nH]1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H4 | Bile acid receptor | 5861 | 6-[4-[[3-(3-chloro-1-methyl-2-oxopyridin-4-yl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]-2-methylphenyl]-1-methylindole-3-carboxylic acid | 7.0 |
Scaffold Activities Statistic