5911 : 3-[benzyl-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]carbamoyl]benzoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 5911 |
| Name | 3-[benzyl-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]carbamoyl]benzoic acid |
| smile | ClC1C=C(C=CC=1N(C(C1C=CC=C(C(=O)O)C=1)=O)CC1C=CC=CC=1)OCC1C(C2C(=CC=CC=2Cl)Cl)=NOC=1C(C)C |
| weight | 650 |
| scaffold ID | 1037 |
| scaffold smile | O=C(c1ccccc1)N(Cc1ccccc1)c1ccc(OCc2conc2-c2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H4 | Bile acid receptor | 5911 | 3-[benzyl-[2-chloro-4-[[3-(2,6-dichlorophenyl)-5-propan-2-yl-1,2-oxazol-4-yl]methoxy]phenyl]carbamoyl]benzoic acid | 10.0 |
Scaffold Activities Statistic