6148 : 2-(N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)methylsulfonamido)pyrimidine-5-carboxylic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6148 |
| Name | 2-(N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)methylsulfonamido)pyrimidine-5-carboxylic acid |
| smile | C1C(C)(C)C2C=CC(N(C3N=CC(C(O)=O)=CN=3)S(C)(=O)=O)=CC=2C(C)(C)C1 |
| weight | 404 |
| scaffold ID | 863 |
| scaffold smile | c1cnc(Nc2ccc3c(c2)CCCC3)nc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR2B1 | Retinoid X receptor alpha | 6148 | 2-(N-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)methylsulfonamido)pyrimidine-5-carboxylic acid | 1.888 |
Scaffold Activities Statistic