6213 : (E)-3-[3-(1-ethyl-4,4,6-trimethyl-2-oxo-3H-quinolin-7-yl)-4-(trifluoromethoxy)phenyl]but-2-enoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6213 |
| Name | (E)-3-[3-(1-ethyl-4,4,6-trimethyl-2-oxo-3H-quinolin-7-yl)-4-(trifluoromethoxy)phenyl]but-2-enoic acid |
| smile | FC(OC1C=CC(/C(=C/C(=O)O)/C)=CC=1C1C(C)=CC2=C(C=1)N(CC)C(CC2(C)C)=O)(F)F |
| weight | 461 |
| scaffold ID | 105 |
| scaffold smile | O=C1CCc2ccc(-c3ccccc3)cc2N1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR2B1 | Retinoid X receptor alpha | 6213 | (E)-3-[3-(1-ethyl-4,4,6-trimethyl-2-oxo-3H-quinolin-7-yl)-4-(trifluoromethoxy)phenyl]but-2-enoic acid | 10.0 |
Scaffold Activities Statistic