6214 : (E)-3-[3-(1-ethyl-4,4,6-trimethyl-2-oxo-3H-quinolin-7-yl)-4-(trifluoromethoxy)phenyl]-2-methylprop-2-enoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6214 |
| Name | (E)-3-[3-(1-ethyl-4,4,6-trimethyl-2-oxo-3H-quinolin-7-yl)-4-(trifluoromethoxy)phenyl]-2-methylprop-2-enoic acid |
| smile | FC(OC1C=CC(/C=C(/C(=O)O)\C)=CC=1C1C(C)=CC2=C(C=1)N(CC)C(CC2(C)C)=O)(F)F |
| weight | 461 |
| scaffold ID | 105 |
| scaffold smile | O=C1CCc2ccc(-c3ccccc3)cc2N1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR2B1 | Retinoid X receptor alpha | 6214 | (E)-3-[3-(1-ethyl-4,4,6-trimethyl-2-oxo-3H-quinolin-7-yl)-4-(trifluoromethoxy)phenyl]-2-methylprop-2-enoic acid | 0.0279 |
Scaffold Activities Statistic