6217 : 3-[3-(1-ethyl-4,4,6-trimethyl-2-oxo-3H-quinolin-7-yl)-4-(trifluoromethoxy)phenyl]-2-methylpropanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6217 |
| Name | 3-[3-(1-ethyl-4,4,6-trimethyl-2-oxo-3H-quinolin-7-yl)-4-(trifluoromethoxy)phenyl]-2-methylpropanoic acid |
| smile | FC(OC1C=CC(CC(C(=O)O)C)=CC=1C1C(C)=CC2=C(C=1)N(CC)C(CC2(C)C)=O)(F)F |
| weight | 463 |
| scaffold ID | 105 |
| scaffold smile | O=C1CCc2ccc(-c3ccccc3)cc2N1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR2B1 | Retinoid X receptor alpha | 6217 | 3-[3-(1-ethyl-4,4,6-trimethyl-2-oxo-3H-quinolin-7-yl)-4-(trifluoromethoxy)phenyl]-2-methylpropanoic acid | 0.76 |
Scaffold Activities Statistic