6221 : 3-[4-(trifluoromethoxy)-3-[4,4,6-trimethyl-2-oxo-1-(2,2,2-trifluoroethyl)-3H-quinolin-7-yl]phenyl]propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6221 |
| Name | 3-[4-(trifluoromethoxy)-3-[4,4,6-trimethyl-2-oxo-1-(2,2,2-trifluoroethyl)-3H-quinolin-7-yl]phenyl]propanoic acid |
| smile | FC(CN1C(CC(C)(C)C2C=C(C)C(C3=C(C=CC(CCC(=O)O)=C3)OC(F)(F)F)=CC1=2)=O)(F)F |
| weight | 503 |
| scaffold ID | 105 |
| scaffold smile | O=C1CCc2ccc(-c3ccccc3)cc2N1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR2B1 | Retinoid X receptor alpha | 6221 | 3-[4-(trifluoromethoxy)-3-[4,4,6-trimethyl-2-oxo-1-(2,2,2-trifluoroethyl)-3H-quinolin-7-yl]phenyl]propanoic acid | 0.0014 |
Scaffold Activities Statistic