6231 : (1S,2S)-2-[3-(1-ethyl-4,4,6-trimethyl-2-oxo-3H-quinolin-7-yl)-4-(trifluoromethoxy)phenyl]cyclopropane-1-carboxylic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6231 |
| Name | (1S,2S)-2-[3-(1-ethyl-4,4,6-trimethyl-2-oxo-3H-quinolin-7-yl)-4-(trifluoromethoxy)phenyl]cyclopropane-1-carboxylic acid |
| smile | FC(OC1C=CC(=CC=1C1C(C)=CC2=C(C=1)N(CC)C(CC2(C)C)=O)[C@H]1C[C@@H]1C(=O)O)(F)F |
| weight | 461 |
| scaffold ID | 246 |
| scaffold smile | O=C1CCc2ccc(-c3cccc(C4CC4)c3)cc2N1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR2B1 | Retinoid X receptor alpha | 6231 | (1S,2S)-2-[3-(1-ethyl-4,4,6-trimethyl-2-oxo-3H-quinolin-7-yl)-4-(trifluoromethoxy)phenyl]cyclopropane-1-carboxylic acid | 0.361 |
Scaffold Activities Statistic