6252 : 2-[2-methyl-4-({4-[4-(piperidine-1-carbonyl)phenyl]-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl}methoxy)phenoxy]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6252 |
| Name | 2-[2-methyl-4-({4-[4-(piperidine-1-carbonyl)phenyl]-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl}methoxy)phenoxy]acetic acid |
| smile | CC1=CC(=CC=C1OCC(O)=O)OCC1=NC(=C(C2=CC=C(C=C2)OC(F)(F)F)S1)C1=CC=C(C(N2CCCCC2)=O)C=C1 |
| weight | 627 |
| scaffold ID | 379 |
| scaffold smile | O=C(c1ccc(-c2nc(COc3ccccc3)sc2-c2ccccc2)cc1)N1CCCCC1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 6252 | 2-[2-methyl-4-({4-[4-(piperidine-1-carbonyl)phenyl]-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl}methoxy)phenoxy]acetic acid | 1.56 |
Scaffold Activities Statistic