6330 : 5-{[4-(4-methoxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}-2,3-dihydro-1-benzofuran-2-carboxylic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6330 |
| Name | 5-{[4-(4-methoxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}-2,3-dihydro-1-benzofuran-2-carboxylic acid |
| smile | COC1=CC=C(C2N=C(SC=2C2=CC=C(C(F)(F)F)C=C2)COC2=CC=C3OC(C(O)=O)CC3=C2)C=C1 |
| weight | 528 |
| scaffold ID | 634 |
| scaffold smile | c1ccc(-c2nc(COc3ccc4c(c3)CCO4)sc2-c2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 6330 | 5-{[4-(4-methoxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}-2,3-dihydro-1-benzofuran-2-carboxylic acid | 10.0 |
Scaffold Activities Statistic