6331 : 2-(2-methyl-4-{[4-(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl]methoxy}phenoxy)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6331 |
| Name | 2-(2-methyl-4-{[4-(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl]methoxy}phenoxy)acetic acid |
| smile | CC1=CC(=CC=C1OCC(O)=O)OCC1=NC(=C(C2=CC=C(C=C2)OC(F)(F)F)S1)C1=CC=C2NC(OC2=C1)=O |
| weight | 573 |
| scaffold ID | 635 |
| scaffold smile | O=c1[nH]c2ccc(-c3nc(COc4ccccc4)sc3-c3ccccc3)cc2o1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 6331 | 2-(2-methyl-4-{[4-(2-oxo-2,3-dihydro-1,3-benzoxazol-6-yl)-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl]methoxy}phenoxy)acetic acid | 10.0 |
Scaffold Activities Statistic