6337 : 2-(4-{[4-(4-methoxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}phenoxy)-2-methylpropanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6337 |
| Name | 2-(4-{[4-(4-methoxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}phenoxy)-2-methylpropanoic acid |
| smile | COC1=CC=C(C2N=C(SC=2C2=CC=C(C(F)(F)F)C=C2)COC2=CC=C(C=C2)OC(C(O)=O)(C)C)C=C1 |
| weight | 544 |
| scaffold ID | 12 |
| scaffold smile | c1ccc(OCc2nc(-c3ccccc3)c(-c3ccccc3)s2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 6337 | 2-(4-{[4-(4-methoxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}phenoxy)-2-methylpropanoic acid | 10.0 |
Scaffold Activities Statistic