6359 : 2-(4-{[(2Z)-3-(4-bromophenyl)-5-[4-(trifluoromethyl)phenyl]pent-2-en-4-yn-1-yl]oxy}-2-methylphenoxy)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6359 |
| Name | 2-(4-{[(2Z)-3-(4-bromophenyl)-5-[4-(trifluoromethyl)phenyl]pent-2-en-4-yn-1-yl]oxy}-2-methylphenoxy)acetic acid |
| smile | CC1=CC(=CC=C1OCC(O)=O)OC/C=C(/C1=CC=C(C=C1)Br)\C#CC1=CC=C(C(F)(F)F)C=C1 |
| weight | 545 |
| scaffold ID | 572 |
| scaffold smile | C(#Cc1ccccc1)C(=CCOc1ccccc1)c1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 6359 | 2-(4-{[(2Z)-3-(4-bromophenyl)-5-[4-(trifluoromethyl)phenyl]pent-2-en-4-yn-1-yl]oxy}-2-methylphenoxy)acetic acid | 10.0 |
Scaffold Activities Statistic