6367 : 2-(2-methyl-4-{[4-(pyrimidin-5-yl)-5-[4-(trifluoromethoxy)phenyl]-1,3-oxazol-2-yl]methoxy}phenoxy)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6367 |
| Name | 2-(2-methyl-4-{[4-(pyrimidin-5-yl)-5-[4-(trifluoromethoxy)phenyl]-1,3-oxazol-2-yl]methoxy}phenoxy)acetic acid |
| smile | CC1=CC(=CC=C1OCC(O)=O)OCC1OC(=C(C2=CN=CN=C2)N=1)C1=CC=C(C=C1)OC(F)(F)F |
| weight | 501 |
| scaffold ID | 9 |
| scaffold smile | c1ccc(OCc2nc(-c3cncnc3)c(-c3ccccc3)o2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 6367 | 2-(2-methyl-4-{[4-(pyrimidin-5-yl)-5-[4-(trifluoromethoxy)phenyl]-1,3-oxazol-2-yl]methoxy}phenoxy)acetic acid | 10.0 |
Scaffold Activities Statistic