6517 : 2-[2-methyl-4-({2-[3-(morpholin-4-yl)prop-1-yn-1-yl]-6-{2-[4-(trifluoromethyl)phenyl]ethynyl}pyridin-4-yl}sulfanyl)phenoxy]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6517 |
| Name | 2-[2-methyl-4-({2-[3-(morpholin-4-yl)prop-1-yn-1-yl]-6-{2-[4-(trifluoromethyl)phenyl]ethynyl}pyridin-4-yl}sulfanyl)phenoxy]acetic acid |
| smile | CC1=CC(=CC=C1OCC(O)=O)SC1=CC(C#CCN2CCOCC2)=NC(C#CC2=CC=C(C(F)(F)F)C=C2)=C1 |
| weight | 567 |
| scaffold ID | 426 |
| scaffold smile | C(#Cc1cc(Sc2ccccc2)cc(C#Cc2ccccc2)n1)CN1CCOCC1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 6517 | 2-[2-methyl-4-({2-[3-(morpholin-4-yl)prop-1-yn-1-yl]-6-{2-[4-(trifluoromethyl)phenyl]ethynyl}pyridin-4-yl}sulfanyl)phenoxy]acetic acid | 0.05 |
Scaffold Activities Statistic