6568 : 4-methyl-N-({4-[1-methyl-1-(trifluoromethanesulfonylcarbamoyl)ethoxy]phenyl}methyl)-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6568 |
| Name | 4-methyl-N-({4-[1-methyl-1-(trifluoromethanesulfonylcarbamoyl)ethoxy]phenyl}methyl)-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide |
| smile | CC1N=C(C2=CC=C(C(F)(F)F)C=C2)SC=1C(NCC1=CC=C(C=C1)OC(C(NS(C(F)(F)F)(=O)=O)=O)(C)C)=O |
| weight | 610 |
| scaffold ID | 174 |
| scaffold smile | O=C(NCc1ccccc1)c1cnc(-c2ccccc2)s1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 6568 | 4-methyl-N-({4-[1-methyl-1-(trifluoromethanesulfonylcarbamoyl)ethoxy]phenyl}methyl)-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carboxamide | 10.0 |
Scaffold Activities Statistic