6677 : 2-[4-({[5-(4-tert-butylphenyl)-1-[2-(morpholin-4-yl)ethyl]-1H-pyrazol-3-yl]formamido}methyl)-2-methylphenoxy]-2-methylpropanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6677 |
| Name | 2-[4-({[5-(4-tert-butylphenyl)-1-[2-(morpholin-4-yl)ethyl]-1H-pyrazol-3-yl]formamido}methyl)-2-methylphenoxy]-2-methylpropanoic acid |
| smile | CC1=CC(=CC=C1OC(C(O)=O)(C)C)CNC(C1C=C(N(N=1)CCN1CCOCC1)C1=CC=C(C(C)(C)C)C=C1)=O |
| weight | 563 |
| scaffold ID | 834 |
| scaffold smile | O=C(NCc1ccccc1)c1cc(-c2ccccc2)n(CCN2CCOCC2)n1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 6677 | 2-[4-({[5-(4-tert-butylphenyl)-1-[2-(morpholin-4-yl)ethyl]-1H-pyrazol-3-yl]formamido}methyl)-2-methylphenoxy]-2-methylpropanoic acid | 25.0 |
Scaffold Activities Statistic