6743 : 2-({4-[(2-{[(4S)-4-hydroxypent-2-yn-1-yl]oxy}-4-[4-(trifluoromethyl)phenoxymethyl]phenyl)sulfanyl]-5,6,7,8-tetrahydronaphthalen-1-yl}oxy)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6743 |
| Name | 2-({4-[(2-{[(4S)-4-hydroxypent-2-yn-1-yl]oxy}-4-[4-(trifluoromethyl)phenoxymethyl]phenyl)sulfanyl]-5,6,7,8-tetrahydronaphthalen-1-yl}oxy)acetic acid |
| smile | C[C@@H](C#CCOC1=CC(=CC=C1SC1=CC=C(C2CCCCC1=2)OCC(O)=O)COC1=CC=C(C(F)(F)F)C=C1)O |
| weight | 587 |
| scaffold ID | 290 |
| scaffold smile | c1ccc(OCc2ccc(Sc3cccc4c3CCCC4)cc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 6743 | 2-({4-[(2-{[(4S)-4-hydroxypent-2-yn-1-yl]oxy}-4-[4-(trifluoromethyl)phenoxymethyl]phenyl)sulfanyl]-5,6,7,8-tetrahydronaphthalen-1-yl}oxy)acetic acid | 1.2 |
Scaffold Activities Statistic