6747 : 2-({4-[(2-{[3-(pyridin-3-yl)prop-2-yn-1-yl]oxy}-4-[4-(trifluoromethyl)phenoxymethyl]phenyl)sulfanyl]-5,6,7,8-tetrahydronaphthalen-1-yl}oxy)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6747 |
| Name | 2-({4-[(2-{[3-(pyridin-3-yl)prop-2-yn-1-yl]oxy}-4-[4-(trifluoromethyl)phenoxymethyl]phenyl)sulfanyl]-5,6,7,8-tetrahydronaphthalen-1-yl}oxy)acetic acid |
| smile | OC(COC1=CC=C(C2CCCCC1=2)SC1=CC=C(C=C1OCC#CC1=CC=CN=C1)COC1=CC=C(C(F)(F)F)C=C1)=O |
| weight | 620 |
| scaffold ID | 925 |
| scaffold smile | C(#Cc1cccnc1)COc1cc(COc2ccccc2)ccc1Sc1cccc2c1CCCC2 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 6747 | 2-({4-[(2-{[3-(pyridin-3-yl)prop-2-yn-1-yl]oxy}-4-[4-(trifluoromethyl)phenoxymethyl]phenyl)sulfanyl]-5,6,7,8-tetrahydronaphthalen-1-yl}oxy)acetic acid | 0.68 |
Scaffold Activities Statistic