6822 : 2-(2-methyl-4-{[4-(pyrimidin-5-yl)-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl]methoxy}phenoxy)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6822 |
| Name | 2-(2-methyl-4-{[4-(pyrimidin-5-yl)-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl]methoxy}phenoxy)acetic acid |
| smile | CC1=CC(=CC=C1OCC(O)=O)OCC1=NC(=C(C2=CC=C(C=C2)OC(F)(F)F)S1)C1=CN=CN=C1 |
| weight | 517 |
| scaffold ID | 429 |
| scaffold smile | c1ccc(OCc2nc(-c3cncnc3)c(-c3ccccc3)s2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 6822 | 2-(2-methyl-4-{[4-(pyrimidin-5-yl)-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl]methoxy}phenoxy)acetic acid | 0.059 |
Scaffold Activities Statistic