6833 : 2-(4-{[4-(2-methoxypyrimidin-5-yl)-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl]methoxy}-2-methylphenoxy)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6833 |
| Name | 2-(4-{[4-(2-methoxypyrimidin-5-yl)-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl]methoxy}-2-methylphenoxy)acetic acid |
| smile | COC1=NC=C(C2N=C(SC=2C2=CC=C(C=C2)OC(F)(F)F)COC2=CC=C(C(=C2)C)OCC(O)=O)C=N1 |
| weight | 548 |
| scaffold ID | 429 |
| scaffold smile | c1ccc(OCc2nc(-c3cncnc3)c(-c3ccccc3)s2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 6833 | 2-(4-{[4-(2-methoxypyrimidin-5-yl)-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl]methoxy}-2-methylphenoxy)acetic acid | 0.034 |
Scaffold Activities Statistic