6837 : 2-[(4-{[4-(4-methoxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}naphthalen-1-yl)oxy]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6837 |
| Name | 2-[(4-{[4-(4-methoxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}naphthalen-1-yl)oxy]acetic acid |
| smile | COC1=CC=C(C2N=C(SC=2C2=CC=C(C(F)(F)F)C=C2)COC2=CC=C(C3=CC=CC=C23)OCC(O)=O)C=C1 |
| weight | 566 |
| scaffold ID | 588 |
| scaffold smile | c1ccc(-c2nc(COc3cccc4ccccc43)sc2-c2ccccc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 6837 | 2-[(4-{[4-(4-methoxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}naphthalen-1-yl)oxy]acetic acid | 2.93 |
Scaffold Activities Statistic