6860 : 2-(5-{[4-(4-methoxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}-1H-indol-1-yl)acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6860 |
| Name | 2-(5-{[4-(4-methoxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}-1H-indol-1-yl)acetic acid |
| smile | COC1=CC=C(C2N=C(SC=2C2=CC=C(C(F)(F)F)C=C2)COC2=CC=C3C(=C2)C=CN3CC(O)=O)C=C1 |
| weight | 539 |
| scaffold ID | 737 |
| scaffold smile | c1cc2cc(OCc3nc(-c4ccccc4)c(-c4ccccc4)s3)ccc2[nH]1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 6860 | 2-(5-{[4-(4-methoxyphenyl)-5-[4-(trifluoromethyl)phenyl]-1,3-thiazol-2-yl]methoxy}-1H-indol-1-yl)acetic acid | 0.34 |
Scaffold Activities Statistic