6874 : 2-[4-({4-[4-(dimethylcarbamoyl)phenyl]-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl}methoxy)-2-methylphenoxy]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6874 |
| Name | 2-[4-({4-[4-(dimethylcarbamoyl)phenyl]-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl}methoxy)-2-methylphenoxy]acetic acid |
| smile | CN(C(C1=CC=C(C2N=C(SC=2C2=CC=C(C=C2)OC(F)(F)F)COC2=CC=C(C(=C2)C)OCC(O)=O)C=C1)=O)C |
| weight | 587 |
| scaffold ID | 12 |
| scaffold smile | c1ccc(OCc2nc(-c3ccccc3)c(-c3ccccc3)s2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 6874 | 2-[4-({4-[4-(dimethylcarbamoyl)phenyl]-5-[4-(trifluoromethoxy)phenyl]-1,3-thiazol-2-yl}methoxy)-2-methylphenoxy]acetic acid | 0.023 |
Scaffold Activities Statistic