6951 : 2-{4-[(1E)-cyclohexyl[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methoxy)imino]methyl]-2-methylphenoxy}acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6951 |
| Name | 2-{4-[(1E)-cyclohexyl[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methoxy)imino]methyl]-2-methylphenoxy}acetic acid |
| smile | CC1=CC(/C(/C2CCCCC2)=N/OCC2SC(C3=CC=C(C(F)(F)F)C=C3)=NC=2C)=CC=C1OCC(O)=O |
| weight | 547 |
| scaffold ID | 420 |
| scaffold smile | c1nc(-c2ccccc2)sc1CON=C(c1ccccc1)C1CCCCC1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C2 | Peroxisome proliferator activated receptor delta | 6951 | 2-{4-[(1E)-cyclohexyl[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methoxy)imino]methyl]-2-methylphenoxy}acetic acid | 0.7 |
Scaffold Activities Statistic