6999 : 2-methyl-2-[(5-methyl-3-{2-[4-(propan-2-yl)-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]ethyl}-1,2-benzoxazol-6-yl)oxy]propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 6999 |
| Name | 2-methyl-2-[(5-methyl-3-{2-[4-(propan-2-yl)-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]ethyl}-1,2-benzoxazol-6-yl)oxy]propanoic acid |
| smile | CC(C1N=C(C2=CC=C(C(F)(F)F)C=C2)SC=1CCC1=NOC2=CC(=C(C=C12)C)OC(C(O)=O)(C)C)C |
| weight | 533 |
| scaffold ID | 1132 |
| scaffold smile | c1nc(-c2ccccc2)sc1CCc1noc2ccccc21 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 6999 | 2-methyl-2-[(5-methyl-3-{2-[4-(propan-2-yl)-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl]ethyl}-1,2-benzoxazol-6-yl)oxy]propanoic acid | 0.91 |
Scaffold Activities Statistic