7313 : 2-{4-[({3-[3-fluoro-4-(trifluoromethyl)phenyl]-1,2,4-thiadiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}-2-methylpropanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 7313 |
| Name | 2-{4-[({3-[3-fluoro-4-(trifluoromethyl)phenyl]-1,2,4-thiadiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}-2-methylpropanoic acid |
| smile | CC1=CC(=CC=C1OC(C(O)=O)(C)C)SCC1=NC(C2=CC=C(C(F)(F)F)C(=C2)F)=NS1 |
| weight | 487 |
| scaffold ID | 411 |
| scaffold smile | c1ccc(SCc2nc(-c3ccccc3)ns2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 7313 | 2-{4-[({3-[3-fluoro-4-(trifluoromethyl)phenyl]-1,2,4-thiadiazol-5-yl}methyl)sulfanyl]-2-methylphenoxy}-2-methylpropanoic acid | 0.64 |
Scaffold Activities Statistic