7417 : 2-[3-(3-{N-[2-cyclopropyl-3-(1,2,4-oxadiazol-3-yl)phenyl]-2-[4-(trifluoromethyl)phenyl]acetamido}propyl)phenoxy]-2-methylpropanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 7417 |
| Name | 2-[3-(3-{N-[2-cyclopropyl-3-(1,2,4-oxadiazol-3-yl)phenyl]-2-[4-(trifluoromethyl)phenyl]acetamido}propyl)phenoxy]-2-methylpropanoic acid |
| smile | CC(C(O)=O)(OC1=CC=CC(=C1)CCCN(C1=CC=CC(C2=NOC=N2)=C1C1CC1)C(CC1=CC=C(C(F)(F)F)C=C1)=O)C |
| weight | 608 |
| scaffold ID | 777 |
| scaffold smile | O=C(Cc1ccccc1)N(CCCc1ccccc1)c1cccc(-c2ncon2)c1C1CC1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 7417 | 2-[3-(3-{N-[2-cyclopropyl-3-(1,2,4-oxadiazol-3-yl)phenyl]-2-[4-(trifluoromethyl)phenyl]acetamido}propyl)phenoxy]-2-methylpropanoic acid | 0.62 |
Scaffold Activities Statistic