7447 : 2-[2-methyl-4-({4-[2-(propan-2-yloxy)pyrimidin-5-yl]-5-[4-(trifluoromethoxy)phenyl]-1,3-oxazol-2-yl}methoxy)phenoxy]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 7447 |
| Name | 2-[2-methyl-4-({4-[2-(propan-2-yloxy)pyrimidin-5-yl]-5-[4-(trifluoromethoxy)phenyl]-1,3-oxazol-2-yl}methoxy)phenoxy]acetic acid |
| smile | CC(OC1=NC=C(C2N=C(OC=2C2=CC=C(C=C2)OC(F)(F)F)COC2=CC=C(C(=C2)C)OCC(O)=O)C=N1)C |
| weight | 559 |
| scaffold ID | 9 |
| scaffold smile | c1ccc(OCc2nc(-c3cncnc3)c(-c3ccccc3)o2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 7447 | 2-[2-methyl-4-({4-[2-(propan-2-yloxy)pyrimidin-5-yl]-5-[4-(trifluoromethoxy)phenyl]-1,3-oxazol-2-yl}methoxy)phenoxy]acetic acid | 0.16 |
Scaffold Activities Statistic