7533 : 2-[(4-{[2-(pent-2-yn-1-yloxy)-4-({[4-(trifluoromethyl)phenyl]amino}methyl)phenyl]sulfanyl}-5,6,7,8-tetrahydronaphthalen-1-yl)oxy]acetic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 7533 |
| Name | 2-[(4-{[2-(pent-2-yn-1-yloxy)-4-({[4-(trifluoromethyl)phenyl]amino}methyl)phenyl]sulfanyl}-5,6,7,8-tetrahydronaphthalen-1-yl)oxy]acetic acid |
| smile | CCC#CCOC1=CC(=CC=C1SC1=CC=C(C2CCCCC1=2)OCC(O)=O)CNC1=CC=C(C(F)(F)F)C=C1 |
| weight | 570 |
| scaffold ID | 1052 |
| scaffold smile | c1ccc(NCc2ccc(Sc3cccc4c3CCCC4)cc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 7533 | 2-[(4-{[2-(pent-2-yn-1-yloxy)-4-({[4-(trifluoromethyl)phenyl]amino}methyl)phenyl]sulfanyl}-5,6,7,8-tetrahydronaphthalen-1-yl)oxy]acetic acid | 10.0 |
Scaffold Activities Statistic