7683 : 4-{[(6-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino]methyl}benzoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 7683 |
| Name | 4-{[(6-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino]methyl}benzoic acid |
| smile | CC(C1ON=C(C2=C(C=CC=C2Cl)Cl)C=1COC1=CC=C(C(C(F)(F)F)=N1)N(CC1=CC=C(C(O)=O)C=C1)C)C |
| weight | 594 |
| scaffold ID | 867 |
| scaffold smile | c1onc(-c2ccccc2)c1COc1ccc(NCc2ccccc2)cn1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 7683 | 4-{[(6-{[3-(2,6-dichlorophenyl)-5-(propan-2-yl)-1,2-oxazol-4-yl]methoxy}-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino]methyl}benzoic acid | 10.0 |
Scaffold Activities Statistic