7733 : 4-{[(6-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino]methyl}benzoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 7733 |
| Name | 4-{[(6-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino]methyl}benzoic acid |
| smile | CN(C1=CC=C(N=C1C(F)(F)F)OCC1=C(C2CC2)ON=C1C1=C(C=CC=C1Cl)Cl)CC1=CC=C(C(O)=O)C=C1 |
| weight | 592 |
| scaffold ID | 607 |
| scaffold smile | c1ccc(CNc2ccc(OCc3c(-c4ccccc4)noc3C3CC3)nc2)cc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C1 | Peroxisome proliferator activated receptor alpha | 7733 | 4-{[(6-{[5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazol-4-yl]methoxy}-2-(trifluoromethyl)pyridin-3-yl)(methyl)amino]methyl}benzoic acid | 10.0 |
Scaffold Activities Statistic