7936 : 2-(benzenesulfonyl)-2-{7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl}-2-fluoro-N-methylacetamide
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 7936 |
| Name | 2-(benzenesulfonyl)-2-{7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl}-2-fluoro-N-methylacetamide |
| smile | C1(C(S(C2=CC=CC=C2)(=O)=O)(C(NC)=O)F)CC2=C(C3=CC(=CC=C3N2)Cl)C1 |
| weight | 421 |
| scaffold ID | 254 |
| scaffold smile | O=S(=O)(CC1Cc2[nH]c3ccccc3c2C1)c1ccccc1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H3 | Oxysterols receptor LXR-alpha | 7936 | 2-(benzenesulfonyl)-2-{7-chloro-1H,2H,3H,4H-cyclopenta[b]indol-2-yl}-2-fluoro-N-methylacetamide | 1.55 |
Scaffold Activities Statistic