7977 : {4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}methanol
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 7977 |
| Name | {4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}methanol |
| smile | OCC1=CC=C(C=C1)CNC1=CC=CC(C2=C(C(C3=CC=CC=C3)=O)C=NC3=C(C(F)(F)F)C=CC=C23)=C1 |
| weight | 513 |
| scaffold ID | 371 |
| scaffold smile | O=C(c1ccccc1)c1cnc2ccccc2c1-c1cccc(NCc2ccccc2)c1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1H2 | Oxysterols receptor LXR-beta | 7977 | {4-[({3-[3-benzoyl-8-(trifluoromethyl)quinolin-4-yl]phenyl}amino)methyl]phenyl}methanol | 2.304 |
Scaffold Activities Statistic