8011 : 3-{4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl)prop-1-yn-1-yl]phenyl}-2-(4-phenylphenyl)propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8011 |
| Name | 3-{4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl)prop-1-yn-1-yl]phenyl}-2-(4-phenylphenyl)propanoic acid |
| smile | CC1OC(C2=CC=CC=C2)=NC=1CC#CC1=CC=C(C=C1)CC(C1=CC=C(C2=CC=CC=C2)C=C1)C(O)=O |
| weight | 498 |
| scaffold ID | 398 |
| scaffold smile | C(#Cc1ccc(CCc2ccc(-c3ccccc3)cc2)cc1)Cc1coc(-c2ccccc2)n1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 8011 | 3-{4-[3-(5-methyl-2-phenyl-1,3-oxazol-4-yl)prop-1-yn-1-yl]phenyl}-2-(4-phenylphenyl)propanoic acid | 2.5 |
Scaffold Activities Statistic