8085 : (2S)-3-(4-{2-[5-methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]ethoxy}naphthalen-1-yl)-2-(2,2,2-trifluoroethoxy)propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8085 |
| Name | (2S)-3-(4-{2-[5-methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]ethoxy}naphthalen-1-yl)-2-(2,2,2-trifluoroethoxy)propanoic acid |
| smile | CC1OC(C2=CC=C(C3=CC=CC=C3)C=C2)=NC=1CCOC1=CC=C(C2=CC=CC=C12)C[C@@H](C(O)=O)OCC(F)(F)F |
| weight | 576 |
| scaffold ID | 901 |
| scaffold smile | c1oc(-c2ccc(-c3ccccc3)cc2)nc1CCOc1cccc2ccccc21 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 8085 | (2S)-3-(4-{2-[5-methyl-2-(4-phenylphenyl)-1,3-oxazol-4-yl]ethoxy}naphthalen-1-yl)-2-(2,2,2-trifluoroethoxy)propanoic acid | 0.038 |
Scaffold Activities Statistic