8086 : (2S)-2-(cyclopropylmethoxy)-3-[4-(2-{5-methyl-2-[4-(propan-2-yl)phenyl]-1,3-oxazol-4-yl}ethoxy)-1-benzothiophen-7-yl]propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8086 |
| Name | (2S)-2-(cyclopropylmethoxy)-3-[4-(2-{5-methyl-2-[4-(propan-2-yl)phenyl]-1,3-oxazol-4-yl}ethoxy)-1-benzothiophen-7-yl]propanoic acid |
| smile | CC(C1=CC=C(C2OC(=C(N=2)CCOC2=CC=C(C3SC=CC2=3)C[C@@H](C(O)=O)OCC2CC2)C)C=C1)C |
| weight | 520 |
| scaffold ID | 943 |
| scaffold smile | c1cc2c(s1)c(CCOCC1CC1)ccc2OCCc1coc(-c2ccccc2)n1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 8086 | (2S)-2-(cyclopropylmethoxy)-3-[4-(2-{5-methyl-2-[4-(propan-2-yl)phenyl]-1,3-oxazol-4-yl}ethoxy)-1-benzothiophen-7-yl]propanoic acid | 0.01 |
Scaffold Activities Statistic