8147 : 4-(4-{[(5Z)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}-2-methoxyphenoxy)-3-(trifluoromethyl)benzonitrile
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8147 |
| Name | 4-(4-{[(5Z)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}-2-methoxyphenoxy)-3-(trifluoromethyl)benzonitrile |
| smile | COC1=CC(=CC=C1OC1=CC=C(C#N)C=C1C(F)(F)F)/C=C1\SC(NC\1=O)=O |
| weight | 420 |
| scaffold ID | 1353 |
| scaffold smile | O=C1NC(=O)C(=Cc2ccc(Oc3ccccc3)cc2)S1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 8147 | 4-(4-{[(5Z)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}-2-methoxyphenoxy)-3-(trifluoromethyl)benzonitrile | 15.0 |
Scaffold Activities Statistic