8164 : (2R)-2-(2-chloro-5-{[3-(6-methyl-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]methyl}phenoxy)propanoic acid
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8164 |
| Name | (2R)-2-(2-chloro-5-{[3-(6-methyl-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]methyl}phenoxy)propanoic acid |
| smile | C[C@H](C(O)=O)OC1=CC(=CC=C1Cl)CN1C(N(C2=NOC3=CC(=CC=C23)C)C2=CC=C(C(F)(F)F)C=C12)=O |
| weight | 546 |
| scaffold ID | 295 |
| scaffold smile | O=c1n(Cc2ccccc2)c2ccccc2n1-c1noc2ccccc21 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 8164 | (2R)-2-(2-chloro-5-{[3-(6-methyl-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]methyl}phenoxy)propanoic acid | 0.077 |
Scaffold Activities Statistic