8165 : (5R)-5-(3-{[3-(6-chloro-1,2-benzoxazol-3-yl)-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl]methyl}phenyl)-5-methyl-1,3-oxazolidine-2,4-dione
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8165 |
| Name | (5R)-5-(3-{[3-(6-chloro-1,2-benzoxazol-3-yl)-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl]methyl}phenyl)-5-methyl-1,3-oxazolidine-2,4-dione |
| smile | C[C@]1(C2=CC=CC(=C2)CN2C(N(C3=NOC4=CC(=CC=C34)Cl)C3=CC=CC=C23)=O)OC(NC1=O)=O |
| weight | 489 |
| scaffold ID | 655 |
| scaffold smile | O=C1NC(=O)C(c2cccc(Cn3c4ccccc4n(-c4noc5ccccc54)c3=O)c2)O1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 8165 | (5R)-5-(3-{[3-(6-chloro-1,2-benzoxazol-3-yl)-2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl]methyl}phenyl)-5-methyl-1,3-oxazolidine-2,4-dione | 0.102 |
Scaffold Activities Statistic