8168 : (5R)-5-(3-{[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]methyl}phenyl)-5-methyl-1,3-oxazolidine-2,4-dione
Ligand Basic Message
| Ligand | Scaffold |
|---|---|
 |  |
| ID | 8168 |
| Name | (5R)-5-(3-{[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]methyl}phenyl)-5-methyl-1,3-oxazolidine-2,4-dione |
| smile | COC1=CC=C2C(N3C(N(C4=CC(C(F)(F)F)=CC=C34)CC3=CC=CC([C@]4(OC(NC4=O)=O)C)=C3)=O)=NOC2=C1 |
| weight | 552 |
| scaffold ID | 655 |
| scaffold smile | O=C1NC(=O)C(c2cccc(Cn3c4ccccc4n(-c4noc5ccccc54)c3=O)c2)O1 |
Ligand Activities
| NR Protein | Protein Name | Ligand ID | Ligand Name | EC 50 |
|---|---|---|---|---|
| NR1C3 | Peroxisome proliferator activated receptor gamma | 8168 | (5R)-5-(3-{[3-(6-methoxy-1,2-benzoxazol-3-yl)-2-oxo-6-(trifluoromethyl)-2,3-dihydro-1H-1,3-benzodiazol-1-yl]methyl}phenyl)-5-methyl-1,3-oxazolidine-2,4-dione | 0.237 |
Scaffold Activities Statistic